Question 1
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One of the greatest benefits of replacing roller bottles with a fixed-bed bioreactor is that one system takes the place of many hundreds (to thousands) of roller bottles. In the case of the fixed-bed bioreactor, we are able to create the surface space in one system by using microcarriers.
As an example, if you replace a 500-roller bottle system with a fixed-bed bioreactor like the iCELLis™ bioreactor, cost savings come from:
•Reduced Manpower: Only one operator is needed to operate only one system. This is a drastic reduction in manpower from the 500 operations that would be needed to accommodate the roller bottles.
•Minimized Space/Accommodation: Only one bioreactor needs to be housed instead of 500 stacked bottles in a roller bottle machine. This creates a 10- to 50- fold savings in the amount of space needed to accommodate the process.
•Decreased Waste: Dramatically decreases the number of aseptic operations and the risk of contamination—less scrap from batches.
The use of the Laboratory Roller Mixer allows you to comply with GMP (Good Manufacturing Practice). This cell culture device in rolling bottles helps you to avoid any risk of contamination by corrosion. It is integrated in a stainless steel trolley and has a stainless steel frame, which also facilitates its use in clean rooms.
A touch-sensitive LCD display is available for setting the cultivation parameters (time, direction of rotation, speed, etc.).
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A built-in battery ensures safe operation in the event of a transfer from one room to another or a power failure. The roller can easily be moved from the filing room to the incubator and back using the large handling bar.
The main technical features of the laboratory roller mixer we offer are as follows
The laboratory roller mixer designed by MGA Technologies can have a configurable capacity (number of levels, number of bottles per level, number of bottles per roller).
The trolley integrating the laboratory roller mixer can be designed to meet all your automation requirements. A dimensional control report is provided to ensure that the bottles can be picked up by robots. Furthermore, in order to ensure the follow-up and traceability of your production, we can propose the integration of RFID tags (option).
If you have specific needs for your laboratory roller mixer, we invite you to request a quote from our sales department. For more information on the equipment, a brochure is available.
If you are looking for more details, kindly visit cell culture roller bottles supplier.